تأثیر هشت هفته تمرین هوازی در آب با و بدون مصرف چای سبز بر فاکتورهای عملکردی کلیوی زنان یائسه غیر فعال

نوع مقاله : مقاله پژوهشی

نویسندگان

1 گروه فیزیولوژی ورزشی، دانشکدةعلوم ورزشی، دانشگاه فردوسی مشهد، مشهد، ایران

2 دکترای تخصصی فیزیولوژی ورزشی، دانشکدةعلوم ورزشی، دانشگاه فردوسی مشهد، مشهد، ایران

3 کارشناس ارشد فیزیولوژی ورزشی، دانشکدةعلوم ورزشی، دانشگاه فردوسی مشهد، مشهد، ایران

چکیده

زمینه و هدف: چاقی در بیماران، کاهش عملکرد کلیه را به دنبال دارد و در افراد سالم، منجر به آسیب‌های کلیوی می‌گردد. هدف از این تحقیق بررسی تأثیر هشت هفته تمرین هوازی در آب با و بدون مصرف چای سبز بر عملکرد کلیوی زنان یائسه غیرفعال می‌باشد.
مواد و روش‌ها: از بین 60 داوطلب، 29زن یائسه غیر فعال که دارای شاخص توده بدنی بالاتر از 25 کیلوگرم بر متر مربع بودند، به طور تصادفی به سه گروه تمرین، مکمل و تمرین+مکمل تقسیم شدند. برنامه تمرین هوازی به‌مدت 8 هفته، هر هفته 3 جلسه و هرجلسه 45 دقیقه با شدت 75-65% ضربان قلب بیشینه اجرا شد. گروه مکمل، روزانه 6 گرم پودر خشک چای سبز را در 600 میلی‌لیتر آب تقریبا جوش ( 80درجه سانتی‌گراد)، یک ساعت قبل از وعده‌های غذایی به‌مدت 8 هفته مصرف کردند. گروه ترکیبی به‌طور هم‌زمان به تمرین‌ و مصرف چای سبز پرداختند.
یافته‌ها: در گروه چای سبز، کراتینین سرم (048/0=p) کاهش معنی‌دار یافت؛ در‌حالی‌که هیچ یک از متغیر‌ها در گروه‌های تمرین (اسیداوریک(432/0=p)، اوره (681/0=p) و کراتینین (1=p)) و تمرین+مکمل (اسیداوریک (597/0=p)، اوره (270/0=p) و کراتینین (235/0=p) تغییر معنی‌داری نداشت. تغییرات بین‌گروهی نیز در هیچ یک از متغیر‌ها معنی‌دار نبود.
نتیجه‌گیری: تمرینات هوازی در آب به مدت هشت هفته به تنهایی و همراه با مصرف چای سبز تأثیری در بهبود عملکرد کلیوی افراد چاق و داری اضافه وزن نداشت، در حالی‌که مصرف چای سبز به تنهایی باعث کاهش سطوح کراتینین و بهبود عملکرد کلیوی گردید.

کلیدواژه‌ها


عنوان مقاله [English]

The effect of aerobic exercise in water with and without green tea consumption on kidney function in sedentary postmenopausal women

نویسندگان [English]

  • Nahid Bijeh 1
  • fahime sadat jamali 2
  • fateme nejati 3
  • mahbobe lotfalizade 3
1 Associated Professor of Department of Sports Physiology, Faculty of sport sciences, Ferdowsi University of Mashhad, Mashhad, Iran
2 PhD Student in Sports Physiology, Faculty of sport sciences, Ferdowsi University of Mashhad, Mashhad, Iran
3 M.Sc. in Sports Physiology, Faculty of sport sciences, Ferdowsi University of Mashhad, Mashhad, Iran
چکیده [English]

Background: Obesity in patients is followed by decreased kidney function and leads to renal damage in healthy people. The aim of this study was to investigate the effect of aerobic exercise with and without green tea consumption on kidney function in sedentary postmenopausal women.
Materials and Methods: Out of 60 volunteers, 29 sedentary postmenopausal women with a body mass index higher than 25 kg/m2 were randomly divided into three groups, exercise, supplement and exercise+supplement. Aerobic exercise program was performed for 8 weeks, 3 sessions per week and each session for 45 minutes at 65-75 % of maximum heart rate. Supplement groups consumed 6 g of green tea powder in 600 ml of almost boiling water (80 °) daily and one hour before their meals for 8 weeks. Combined group performed exercise and consumed supplement, simultaneously.
Results: In supplement group, creatinine levels (p=0.048) decreased significantly; While none of the variables in exercise group (uric acid (p=0.432), urea (p=0.681) and creatinine (p=1)) and exercise+supplement group (uric acid (p=0.597), urea (p=0.270) and creatinine (p=0.235)) had no significant change. Between groups changes in any of the variables was not significant too.
Conclusion: Eight weeks of aerobic exercises in water alone and in combination with green tea consumption did not improve renal function in obese and overweight postmenopausal women, while green tea consumption alone decreased serum creatinine and improved renal function.

کلیدواژه‌ها [English]

  • Aerobic Exercise
  • Creatinine
  • green tea
  • Urea
  • Uric acid 
[1] Kovesdy CP, Furth S, Zoccali C, World Kidney Day Steering Committee. Obesity and kidney disease: hidden consequences of the epidemic. J Endocrinology, Metabolism and Diabetes of South Africa.2017; 22(1):5-11.
[2]Mortazavi M, Rouhi L. Effect of pomegranate peel extract on the prevention of ethylene glycol induced kidney stones in Wistar rats. Pharm Sci.2014; 6(3):149-53. [in Persian]
[3] Patrica J. Creatine metabolism and psychiatric disorders: does creatine supplementation have therapeutical value? Neuroscience and behavioral reviewes.2012; 36: 1442-62.
[4] Nowak R, Buryta R, Kostrzewa-Nowak D. The search for new diagnostic markers of metabolic response to aerobic exercise: analysis of creatinine, urea, and uric acid levels in football players. Trends in Sport Sciences.2016; 23(4): 121-32.
[5] Ziaee A, Shikhileslami H, Sarreshtehdari M, Javadi M, Khoeini H. Association of uric acid and albuminuria in patients with type 2 diabetes. Qazvin Univ Med Sci J.2008; 1(46):16-20. [in Persian]
[6] Lippi G.Acute variation of estimated glomerular filtration rate following a half-marathon run. Int J Sports med.2008; 29: 948-51.
[7] Sahin K, Tuzcu M, Orhan C, Sahin N, Akdemir F, Pala R, Juturu V. Dietary Mango Ginger May Enhance the Exercise Performance and Reduces Lipid Profile when Combined with Treadmill Running in a Rat Model. The FASEB J.2017; 1(31):646-78.
[8] Clarkson PM, Hubal MJ. Exercise-induced muscle damage in humans. Am J Phys Med.2002; 8(1): 52–69.
[9]Kayacan Y, Kaya Y, Makaracı Y. Excretionof creatinine, uric acidandmicro proteinsby generalbody massageappliedafterexercise. European Journal of Physical Education and Sport Science.2017; 3(6): 36-46.
[10]Straznicky NE, Grim, MT, Lambert EA, Eikelis N, Dawood T, Lambert GW, et al. Exercise augments weight loss induced improvementin renal function in obese metabolic ‌syndrome individuals. J Hypertens.2011; 29: 553-64.
[11]Hoseinikakhak A, Amiriparsa T, Azarnive MS, Hamedinia MR, Khademosharie M. Effects of aerobictraining and subsequent detraining on renal indices in obese girls.J Sport Biosci 2012; 11(4):89-102.[in Persian]
[12] Kayacan Y, Kaya Y, Makaracı Y. Excretion Creatinine, Uric Acid and Microproteins by General Body Masage Applied After Exercise. J of Physical Education and Sport Science.2017; 30(12): 233-46.
[13] Roh E, Kim JE, Kwon JY, Park JS, Bode AM, Dong Z, Lee KW. Molecular mechanisms of green tea polyphenols with protective effects against skin photoaging. Critical reviews in food science and nutrition.2017; 57(8): 1631-7.
[14] Ogle N. Green tea Camellia Sinensis. AJMH.2009; 21(3): 44 –7.
[15] Jamshidi Z, Taheri E, Mohammadi M, Koochsfahani H. Protective effect of green tea on kidney tissues and blood indices of kidney function in male rats treated with paclitaxel. Medicinal Plants J.2017; 10(4): 47-59. [in Persian]
[16] Palmer BF, Clegg DJ. Gonadal dysfunction in chronic kidney disease. Reviews in Endocrine and Metabolic Disorders.2017; 18(1):117-30.
[17] Wang H, Li D, Hu Z, Zhao S, Zheng Z, Li W. Protective effects of green tea polyphenol against renal injury through ROS-mediated JNK-MAPK pathway in lead exposed rats. Molecules and cells.2016; 39(6): 508-16.
[18] Ahmed M. Effect of some food additives consumption on the body weight and toxicity and the possible ameliorative role of green tea extract. Sciences.2016; 6(4); 716-30.
[19] Nasri H, Ahmadi A, Baradaran A, Nasri P, Hajian S, Pour-Arian A, Rafieian-Kopaei M. A biochemical study on ameliorative effect of green tea (Camellia sinensis) extract against contrast media induced acute kidney injury. Journal of renal injury prevention.2014; 3(2); 47-55.[in Persian]
[20] Xie X, Yi W, Zhang P, Wu N, Yan Q, Yang H, Tian C, Xiang S, Du M, Getachew Assefa E, Zuo X. Green Tea Polyphenols, Mimicking the Effects of Dietary Restriction, Ameliorate High-Fat Diet-Induced Kidney Injury via Regulating Autophagy Flux. Nutrients, 2017; 9(5):497-507.
[21] Hamadouche N, Hadi A. The protective effect of green tea extract on lead induced oxidative and damage on rat kidney. International Journal of Pharmacy and Biological Sciences. 2015; 6(2): 97-107.
[22] Samavati.Sharif MA, Siavashi H. Effect of 10 weeks aerobic training on glomerular filtration and urea, creatinine and uric acid levels in old men with type 2 diabetes. Sports biology Sciences J.2016; 7(4): 591-79. [in Persian]
[23] Ramezanpour MR, Hejazi M, Motaghishahri S, Kianmehr M, Motaghishahri MR. Comparison of the effect of periodic, continuous and parallel aerobic exercise on urea, uric acid and urine creatinine levels. Q Horizon Med Sci, 2013.19(3): 138-41. [in Persian]
[24] Zhu C, Tai LL, Wan XC, Li DX, Zhao YQ, Xu Y. Comparative effects of green and black tea extracts on lowering serum uric acid in hyperuricemic mice. Pharmaceutical biology.2017; 55(1):2123-8.
[25] Elena G, Klans L. Leukocyte recruitment and vascular injury in diabetic nephropathy. Am Soci Nephro.2006; 17(5): 368-77.
[26] Keah SH, Chng Ks. Exercise-induced rhabdomyolises with acute renal failur after strenuous pus-ups. Malaysian Family Physician.2009; 4(1): 37-44.
[27] Garnett LE, West SL. Exercise in Men and Women with Pre-Dialysis Chronic Kidney Disease: A Review. J of Undergraduate Studies at Trent (JUST), 2017; 5(1):18-26.
[28] Gaeini AA, Hoseini A, Samadi A. The comparison of two soccer and semi-soccer protocol induced excretion of urinary protein in adolescent male soccer players. JMPA.2011; 1(2): 99-106. [in Persian]
[29] Sokal P, Jastrzebski Z, Jaskulska E, Sokal K, Jastrzebska M, Radziminski L, et al. Differences in Blood Urea and Creatinine Concentrations in Earthed and Unearthed Subjects during Cycling Exercise and Recovery. Hindawi.2013; 1(6): 382-6.
[30] Ikeda T,Gomi T, Sasaki Y. Effects of swim training on blood pressure, catecholamines and prostaglandins in spontaneously hypertensive rats. Japanese heart J.1994; 35(3): 205-11.