بررسی اثربخشی مکمل چای سبز در مقایسه با مکمل‌های فیبر، کافئین و ال‌کارنیتین بر کاهش وزن در افراد چاق (یک متاآنالیز شبکه‌ای)

نوع مقاله : مقاله پژوهشی

نویسندگان

1 کمیته تحقیقات دانشجویی، گروه تغذیه بالینی، دانشکده تغذیه و صنایع غذایی، دانشگاه علوم پزشکی شهید بهشتی، تهران، ایران.

2 مرکز پژوهش های دانشجویی ، دانشگاه علوم پزشکی تهران ، تهران ، ایران.

3 مرکز پژوهش های دانشجویی ، دانشگاه علوم پزشکی تهران ، تهران ، ایران

4 کمیته تحقیقات دانشجویی، گروه تغذیه بالینی، دانشکده تغذیه و صنایع غذایی، دانشگاه علوم پزشکی شهید بهشتی، تهران، ایران

چکیده

زمینه  تاکنون مطالعه‌ای، میزان اثربخشی جامع مکمل چای سبز را نسبت به فیبر، کافئین و ال‌کارنیتین بر کاهش وزن افراد چاق تعیین نکرده است. بنابراین هدف از این مطالعه، ارزیابی جامع مکمل چای، فیبر، کافئین و ال‌کارنیتین بر کاهش وزن در افراد چاق می‌باشد.
روش کار پایگاه‌های اطلاعاتی پابمد، اسکوپوس و کاکرن تا تاریخ آبان‌ماه 1397 جستجو شد. از روش pairwise برای مقایسه اختلاف میانگین کاهش وزن داروها در دو روش مستقیم (مقایسه داروها با گروه کنترل) و غیرمستقیم (مقایسه داروها با یکدیگر) استفاده شد.
یافته‌ها مطالعه حاضر که بر روی 73 مطالعه بالینی با جمعیت 3921 (2002 نفر گروه مداخله و 1919 گروه کنترل) نشان داد که مکمل کافئین (88/0- کیلوگرم، فاصله اطمینان 60/2- تا 84/0-) و بعد از آن مکمل ترکیبی کافئین با کاتچین (74/0- کیلوگرم، فاصله اطمینان 70/1- تا 21/0-)، چای (61/0- کیلوگرم، فاصله اطمینان 33/1- تا 11/0-)، فیبر(31/0- کیلوگرم، فاصله اطمینان 79/0- تا 17/0-)، به ترتیب بیشترین تأثیر را در کاهش وزن در مقایسه با گروه دارونما دارند، به هر حال مکمل کارنیتین، تأثیری بر کاهش وزن نداشت.
نتیجه‌گیری مطالعه حاضر نشان داد که اثربخشی مکمل چای سبز در کاهش وزن در مقایسه با فیبر و کارنیتین، بیشتر و در مقایسه با کافئین و ترکیب کافئین با کاتچین، کمتر می‌باشد.

کلیدواژه‌ها


عنوان مقاله [English]

A Survey on Clinical Effectiveness of Green Tea Supplementation Compared to Fiber, Caffeine and L-carnitine Supplements on Weight Loss: a Network Meta-Analysis

نویسندگان [English]

  • Ammar salehi 1
  • Hamed kord Varkaneh 2
  • mohammadreza emami 3
  • mina ahmadzade 2
  • HANIEH IRANI 4
1 Student Research Committee, Department of Clinical Nutrition and Dietetics, Faculty of Nutrition and Food Technology, Shahid Beheshti University of Medical Sciences, Tehran, Iran
2 Students’ Scientific Research Center, Tehran University of Medical Sciences, Tehran, Iran
3 Students’ Scientific Research Center, Tehran University of Medical Sciences, Tehran, Iran
4 Student Research Committee, Department of Clinical Nutrition and Dietetics, Faculty of Nutrition and Food Technology, Shahid Beheshti University of Medical Sciences, Tehran, Iran
چکیده [English]

Introduction: No study compared the effectiveness of the green tea, fiber, caffeine and L-carnitine on weight loss in individuals. Therefore, the aim of this study was to evaluate the efficacy of green tea, fiber, caffeine and L-carnitine in clinical aspects of people.
 Materials and Methods: The databases of Pubmed, Scopus and Cochran were searched up to November 2018. The pairwise method was used to compare the difference between the mean weight loss of drugs in two direct methods (comparison of drugs with the control group) and non-direct (Compare medications together).
Results: The present study performed on 73 clinical studies with a cumulative population of 3921, showed that caffeine (-0.88 kg; -2.60 to -0.84), caffeine + catechine (-0.74 kg; -1.70 to 0.21), green tea (-0.61 kg; -1.33 to -0.11), fiber (-0.31 kg; -0.79 to -0.17), respectively, had the most effect on weight loss compared with the placebo group. In addition, carnitine supplementation did not effect on weight loss.
Conclusion: The present study indicated that green tea supplementation had a lower effect on weight loss compared with caffeine and caffeine+catechin, and had a greater effect on weight loss compared with fiber and carnitine.

کلیدواژه‌ها [English]

  • green tea
  • fiber
  • caffeine
  • L-carnitine and weight Loss
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دوره 27، شماره 3
مرداد و شهریور 1399
صفحه 363-372
  • تاریخ دریافت: 18 فروردین 1398
  • تاریخ بازنگری: 02 اردیبهشت 1398
  • تاریخ پذیرش: 01 خرداد 1398
  • تاریخ اولین انتشار: 01 شهریور 1399